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Cardiovascular determinants of prognosis in normotensive hemodialysis patients
I-Feng Lin; Shao-Yuan Chuang; Wen-Chung Yu; Chen-Huan Chenb; Yao-Ping Lin
BMC Nephrology,13,1(2012-09-20)
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摘要:

Background

Normotension has been hold to be the goal of hemodialysis. It remains obscure which cardiovascular parameter determines the prognosis in these normotensive hemodialysis patients.

Methods

We prospectively enrolled 145 hemodialysis patients, who had attained normotension without anti-hypertensive medications, and followed them for 72.6????????28.5 months. Important cardiovascular parameters were obtained at enrollment. Predictors for all-cause and cardiovascular mortalities were identified with the Cox model.

Results

There were 45 (18 cardiovascular/27 non-cardiovascular) deaths occurred during follow-up. Age, diabetes, left ventricular mass index (LVMI), left ventricular ejection fraction (LVEF), carotid intima-media thickness (CIMT), and aortic pulse wave velocity (PWV) were significant predictors for all-cause and cardiovascular mortalities. After adjustment for age and diabetes, only LVEF was significantly associated with all-cause mortality. LVEF was significantly associated with cardiovascular mortality. LVEF remained as a significant independent predictor of cardiovascular death after adjusting for age, diabetes, LVMI, CIMT, or PWV, respectively.

Conclusion

LVEF is the independent predictor for all-cause and cardiovascular mortalities in the normotensive hemodialysis patients.

关键词:Arterial stiffness, End-stage renal disease, Hypertension, Left ventricular function, Mortality

出版者:BioMed Central Ltd
出版日期:2012-09-20
资源类型:期刊论文
学科分类:Urology;Nephrology
语种:en
授权许可:http://creativecommons.org/licenses/by/2.0/
本地全文:http://gooa.las.ac.cn/external/index?type=-1&pid=1083096
内容提供者:开放获取论文一站式发现平台(GoOA)

推荐引用方式:I-Feng Lin,Shao-Yuan Chuang,Wen-Chung Yu, et al. Cardiovascular determinants of prognosis in normotensive hemodialysis patients[J]. BMC Nephrology,2012,13(1)

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